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MYOG
Anti-MYOG Recombinant Antibody Products
- AbPlus™ Anti-MYOG Magnetic Beads (F12B) (VS-0424-XY197)
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- Target: MYOG
- Target Species: Human, Mouse, Rat
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle.
Protein class
Cancer-related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Skeletal myocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HSkMC, RH-30)
Interaction
Homodimer and heterodimer with E12; heterodimerization enhances MYOG DNA-binding and transcriptional activities. Interacts with SMARCA4/BRG1/BAF190A. Interacts (via C-terminal region) with SSRP1 and SUPT16H; the interaction is indicative of an interaction with the FACT complex (By similarity). Interacts with CSRP3.
Molecular function
Activator, Developmental protein, DNA-binding
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