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NDN
Anti-NDN Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA, IF, IHC, IP
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- Recombinant Mouse Anti-Human NDN Antibody (MOB-1327MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress growth in postmitotic neurons.
Protein class
Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Leydig cells, Peritubular cells, Theca cells)
Immune cell specificity
Immune cell enhanced (plasmacytoid DC)
Cell line specificity
Cell line enhanced (AF22, ASC diff, HSkMC, NTERA-2, SuSa, U-2 OS, U-266/70, U-266/84)
Interaction
Binds to the transactivation domains of E2F1 and p53. Binds also SV40 large T antigen and adenovirus E1A. Interacts with nucleobindin 1 and 2 (By similarity).
Molecular function
DNA-binding
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