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Nectin2

Anti-Nectin2 Products

Recombinant Mouse Anti-Nectin2 Antibody (FAPAB-0338-CN)
- Derivation: Serum
- Species Reactivity: Xenopus
- Type: Mouse IgG
- Application: WB
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Recombinant Rabbit Anti-NECTIN2 Monoclonal Antibody (JG39-64) (MRO-1070-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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Mouse Anti-Nectin2 Antibody, mRNA (FAPAB-0338-CN-mRNA)
- Species Reactivity: Xenopus
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Rabbit Anti-NECTIN2 Recombinant Antibody (clone JG39-64) (VS3-WK496)
- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
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Recombinant Rabbit Anti-NECTIN2 Antibody (clone R07-7G6) (VS3-FY1020)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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Rabbit Anti-NECTIN2 Recombinant Antibody (clone R06-8F3) (VS3-FY2044)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IP
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AbPlus™ Anti-NECTIN2 Magnetic Beads (VS-0724-YC1270) (VS-0724-YC1270)
- Target: NECTIN2
- Target Species: Human
- Application: IP, Protein Purification
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AbPlus™ Anti-Nectin2 Magnetic Beads (VS-0724-YC1308) (VS-0724-YC1308)
- Target: Nectin2
- Target Species: Mouse
- Application: IP, Protein Purification
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Rabbit Anti-NECTIN2 Recombinant Antibody (VS13-YC780) (VS13-YC780)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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Recombinant Anti-Nectin2 Vesicular Antibody, EV Displayed (VS-0425-YC681) (VS-0425-YC681)
- Species Reactivity: Xenopus
- Target: Nectin2
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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Anti-NECTIN2 Immunohistochemistry Kit (VS-0525-XY4764)
- Species Reactivity: Human
- Target: NECTIN2
- Application: IHC
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Anti-Mouse NECTIN2 Immunohistochemistry Kit (VS-0525-XY4765)
- Species Reactivity: Human, Mouse, Rat
- Target: NECTIN2
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Predicted to enable ATP binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple sclerosis. Orthologous to human PVR (PVR cell adhesion molecule) and NECTIN2 (nectin cell adhesion molecule 2).

Protein class

CD markers, Plasma proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Pancreatic endocrine cells, Ductal cells, Exocrine glandular cells, Adipocytes, Glandular and luminal cells)

Immune cell specificity

Immune cell enhanced (eosinophil)

Cell line specificity

Low cell line specificity

Interaction

Can form trans-heterodimers with NECTIN3 (By similarity). Interacts with CD226 or with PVRIG; these interactions are competitive and have a differential functional outcome on T-cell activation, either positive or negative, respectively. Binds with low affinity to TIGIT. (Microbial infection) Interacts with herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV) envelope glycoprotein D (PubMed:11602758, PubMed:9657005).

Molecular function

Host cell receptor for virus entry, Receptor

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