+ Filter
Loading...
PDGFRL
Anti-PDGFRL Recombinant Antibody Products
CompareCan't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
Protein class
Disease related genes
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Fibroblasts, Leydig cells, Peritubular cells, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AN3-CA, BJ hTERT+, HSkMC)
Interaction
Forms a complex composed of PDGFRL, TNK2 and GRB2.
More Types Infomation