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For Research Use Only. Not For Clinical Use.
Enzymes
Intracellular
Cell type enhanced (Late spermatids, Early spermatids)
Low immune cell specificity
Low cell line specificity
Interacts with AR, AXIN1, GATA2, LEF1, TP53 and STAT1 (IFNG-induced) (PubMed:11248056, PubMed:11388671, PubMed:11439351, PubMed:12223491, PubMed:12750312). Interacts with TICAM1 (PubMed:15251447). Interacts with KLF8; the interaction results in SUMO ligation and repression of KLF8 transcriptional activity and of its cell cycle progression into G(1) phase (PubMed:16617055). Interacts with MTA1 (PubMed:21965678). Interacts with PRDM1/Blimp-1 (PubMed:28842558). Interacts with TRIM32 upon treatment with UVB and TNF-alpha (By similarity).
DNA-binding, Repressor, Transferase