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PLA2G7

Anti-PLA2G7 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.
Protein class

Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets

Predicted location

Secreted

Single cell type specificity

Group enriched (Hofbauer cells, Macrophages)

Immune cell specificity

Immune cell enhanced (classical monocyte)

Cell line specificity

Cell line enhanced (NTERA-2, PC-3, RT4, U-2 OS)

Molecular function

Hydrolase

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