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PNMT
Anti-PNMT Recombinant Antibody Products
- Mouse Anti-NHP PNMT Recombinant Antibody (clone OTI1D2) (VS-1024-XY398)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate, Rat
- Type: Mouse IgG2b
- Application: WB, IHC, IF
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For Research Use Only. Not For Clinical Use.
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Skeletal myocytes, Hepatic stellate cells, Endometrial ciliated cells, Breast glandular cells, Erythroid cells, Breast myoepithelial cells, Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HEL, K-562, NB-4, NTERA-2, SCLC-21H, SH-SY5Y)
Molecular function
Methyltransferase, Transferase
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