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PTPRJ
Anti-PTPRJ Recombinant Antibody Products
- CytoStream™ Mouse Anti-PTPRJ Recombinant Antibody (clone A3) (VS-0225-XY187)
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- Species Reactivity: Human
- Type: Mouse IgG1, kappa
- Application: FC
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For Research Use Only. Not For Clinical Use.
PTPRJ (Protein Tyrosine Phosphatase Receptor Type J) encodes a receptor-type phosphatase involved in regulating cell adhesion, growth, and migration. It is expressed in various tissues, including endothelial and neuronal cells. PTPRJ is involved in modulating vascular development, immune responses, and tumor progression, making it a potential therapeutic target in cancer and vascular diseases.
Protein class
CD markers, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Microglial cells, Oligodendrocytes, Inhibitory neurons)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (RPTEC TERT1)
Interaction
Monomer. Interacts with CTNNB1 (phosphorylated) and JUP (phosphorylated). Interacts with FLT3 (phosphorylated). Interacts with GAB1 and GRB2.
Molecular function
Hydrolase, Protein phosphatase
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