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RPS6KA5
Anti-RPS6KA5 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including histone-serine phosphorylation; positive regulation of histone modification; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Oligodendrocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1)
Interaction
Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells which transiently dissociates following mitogenic stimulation. Also associates with MAPK14/p38-alpha. Activated RPS6KA5 associates with and phosphorylates the NF-kappa-B p65 subunit RELA. Interacts with CREBBP and EP300.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
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