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RTN1
Anti-RTN1 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IHC
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- Species Reactivity: Hamster, Human, Mouse, Rat
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB
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- Species Reactivity: Hamster, Human, Mouse, Rat
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB
Compare
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- Species Reactivity: Hamster, Human, Mouse, Rat
- Type: Mouse IgG1
- Application: ICC, IHC-Fr, IHC-P, WB
Compare
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- Species Reactivity: Human, Monkey, Rabbit
- Type: Mouse IgG1
- Application: FC, ICC, IHC-Fr, IHC-P, WB
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For Research Use Only. Not For Clinical Use.
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants.
Protein class
Plasma proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Oligodendrocytes, Horizontal cells, Oligodendrocyte precursor cells)
Immune cell specificity
Group enriched (myeloid DC, intermediate monocyte, classical monocyte)
Cell line specificity
Group enriched (HEL, SCLC-21H, SH-SY5Y)
Interaction
Interacts with NDRG1 (PubMed:15922294). Interacts with BACE1 (PubMed:15286784). [Isoform RTN1-A]: Interacts with TMEM33 (PubMed:25612671). [Isoform RTN1-C]: Interacts with UGCG; regulates the ceramide glucosyltransferase activity of UGCG (PubMed:12873973).
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