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S100P
Anti-S100P Recombinant Antibody Products
- Mouse Anti-S100P Recombinant Antibody (TAB-0224CL) (TAB-0224CL)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Block, Neut
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- Mouse Anti-S100P Recombinant Antibody; scFv Fragment (TAB-0224CL-S(P)) (TAB-0224CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, Block, Neut
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- Mouse Anti-S100P Recombinant Antibody; Fab Fragment (TAB-0224CL-F(E)) (TAB-0224CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, Block, Neut
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Urothelial cells, Syncytiotrophoblasts, Gastric mucus-secreting cells, Club cells)
Immune cell specificity
Group enriched (neutrophil, basophil, eosinophil)
Cell line specificity
Cell line enhanced (BEWO, Hep G2, hTCEpi, OE19, RT4, SK-BR-3)
Interaction
Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.
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