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SFTPA1
Anti-SFTPA1 Recombinant Antibody Products
- Recombinant Llama Anti-Rat Sftpa1 Single Domain Antibody (HPAB-0491-YJ-VHH) (HPAB-0491-YJ-VHH)
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- Derivation: Phage library
- Species Reactivity: Rat
- Type: Llama VHH
- Application: ELISA, WB, IHC
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- Recombinant Llama Anti-Rat Sftpa1 Single Domain Antibody (HPAB-0492-YJ-VHH) (HPAB-0492-YJ-VHH)
-
- Derivation: Phage library
- Species Reactivity: Rat
- Type: Llama VHH
- Application: ELISA, WB, IHC
Compare
- Recombinant Llama Anti-Rat Sftpa1 Single Domain Antibody (HPAB-0493-YJ-VHH) (HPAB-0493-YJ-VHH)
-
- Derivation: Phage library
- Species Reactivity: Rat
- Type: Llama VHH
- Application: ELISA, WB, IHC
Compare
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For Research Use Only. Not For Clinical Use.
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Protein class
Disease related genes, Human disease related genes
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Alveolar cells type 2)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enriched (RPMI-8226)
Interaction
Oligomeric complex of 6 set of homotrimers. (Microbial infection) Binds M. bovis cell surface protein Apa via its glycosylated sites; probably also recognizes other bacterial moieties. (Microbial infection) Binds to the S. aureus extracellular adherence protein, Eap, thereby enhancing phagocytosis and killing of S. aureus by alveolar macrophages.
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