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SGK3

Anti-SGK3 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Breast glandular cells, monocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (T-47d)

Interaction

Interacts with GSK3B and FLII. Interacts with PDPK1 in a phosphorylation-dependent manner.

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

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