+ Filter
Loading...
SNCAIP
Anti-SNCAIP Recombinant Antibody Products
CompareCan't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinsons disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2011]
Protein class
Disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Early spermatids, Inhibitory neurons, Endometrial stromal cells, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enhanced (AF22, BJ hTERT+, HBF TERT88, OE19, RPMI-8226)
Interaction
Homodimer (Probable). Heterodimer of isoform 1 and isoform 2 (Probable). Interacts with SIAH1, SIAH2, SNCA, RNF19A AND PRKN. Isoform 2 has a strong tendency to form aggregates and can sequester isoform 1.
More Types Infomation