+ Filter
Loading...
Custom Services order now ship next day

ST14

Loading...

Anti-ST14 Products

View More Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Background

Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within epithelial cell morphogenesis involved in placental branching and neural tube closure. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase).
Protein class

Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Distal enterocytes, Paneth cells, Urothelial cells, Proximal enterocytes, Undifferentiated cells)

Immune cell specificity

Immune cell enriched (plasmacytoid DC)

Cell line specificity

Cell line enhanced (CACO-2, CAPAN-2, HaCaT, OE19, RPMI-8226, SK-BR-3, T-47d, U-698)

Interaction

Interacts with CDCP1. May interact with TMEFF1.

Molecular function

Hydrolase, Protease, Serine protease

More Types Infomation
Go to compare

Go to compare