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STX6
Anti-STX6 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
STX6 (Syntaxin 6) is a Protein Coding gene. Diseases associated with STX6 include tauopathy. Among its related pathways are Normal wtCFTR traffic / ER-to-Golgi and Nicotine Pathway (Dopaminergic Neuron), Pharmacodynamics. GO annotations related to this gene include syntaxin binding and SNAP receptor activity. An important paralog of this gene is STX10.
Protein class
Plasma proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (PubMed:17159904). Binds EEA1 (By similarity). Interacts with VPS45A (By similarity). Interacts with MARCHF2; the interaction promotes MARCHF2-mediated ubiquitination and degradation of CFTR (PubMed:23818989). Interacts with MARCHF3 (By similarity). Interacts with GOPC (PubMed:11384996). Interacts with UHRF1BP1L (via C-terminal coiled-coil domain) (PubMed:20163565). Interacts with BAIAP3; this interaction is increased in the presence of calcium (PubMed:28626000).
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