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TNFRSF10D

Anti-TNFRSF10D Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway
Protein class

Cancer-related genes, CD markers

Predicted location

Membrane

Single cell type specificity

Group enriched (Adipocytes, Gastric mucus-secreting cells, Endothelial cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HUVEC TERT2, LHCN-M2, WM-115)

Molecular function

Receptor

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