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TNFSF18

Functional Antibody Products Formats

Anti-TNFSF18 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Predicted location

Intracellular

Single cell type specificity

Group enriched (Basal squamous epithelial cells, Hofbauer cells, Squamous epithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (EFO-21, HUVEC TERT2, TIME)

Interaction

Homodimer (By similarity). Homotrimer.

Molecular function

Cytokine

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