UBE2M

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-UBE2M Recombinant Antibody Products

AbPlus™ Anti-UBE2M Magnetic Beads (VS-0724-YC804) (VS-0724-YC804)
- Target: UBE2M
- Target Species: Human, Mouse
- Application: IP, Protein Purification
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AbPlus™ Anti-UBE2M Magnetic Beads (VS-0724-YC803) (VS-0724-YC803)
- Target: UBE2M
- Target Species: Human
- Application: IP, Protein Purification
Compare

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For Research Use Only. Not For Clinical Use.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HEK93)

Interaction

Interacts with UBA3 and RBX1. Interacts (N-terminally acetylated form) with (via DCUN1 domain) DCUN1D1, DCUN1D2, DCUN1D3, DCUN1D4 and DCUN1D5 (PubMed:23201271, PubMed:28581483).

Molecular function

Transferase

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