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UCHL1
Anti-UCHL1 Recombinant Antibody Products
- Chicken Anti-UCHL1 Polyclonal IgY (BRD-0615MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Chicken Anti-PGP9.5 Polyclonal IgY (BRD-0800MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: ICC, IF, IHC, WB
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
Protein class
Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal tubular cells, Excitatory neurons, Horizontal cells, Inhibitory neurons, Collecting duct cells, Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (EFO-21, SCLC-21H, U-251 MG, U-266/84, U-87 MG)
Interaction
Monomer. Homodimer. Interacts with SNCA (By similarity). Interacts with COPS5.
Molecular function
Hydrolase, Protease, Thiol protease
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