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WIPI1
Anti-WIPI1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Syncytiotrophoblasts)
Immune cell specificity
Group enriched (eosinophil, basophil)
Cell line specificity
Cell line enhanced (ASC diff, HHSteC, HSkMC, SK-MEL-30)
Interaction
Interacts with androgen receptor (AR) and the estrogen receptors ESR1 and ESR2 (PubMed:15602573). Interacts with WIPI2 (PubMed:28561066). Interacts with WDR45 (PubMed:28561066). Interacts with ATG16L1 (PubMed:28561066). May interact with NUDC (PubMed:28561066).
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