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WWP2
Anti-WWP2 Recombinant Antibody Products
- Recombinant Anti-human WWP2 Antibody (MOB-1054)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
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- Recombinant Human Anti-human WWP2 Antibody (MHH-1054)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: RIA, ELISA, FuncS
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- Human Anti-WWP2 Recombinant Antibody (HPAB-0088-WJ) (HPAB-0088-WJ)
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- Derivation: Hybridoma
- Species Reactivity: S. aureus
- Type: Human IgG
- Application: ELISA
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- Human Anti-WWP2 Recombinant Antibody; scFv Fragment (HPAB-0088-WJ-S(P)) (HPAB-0088-WJ-S(P))
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- Derivation: Hybridoma
- Species Reactivity: S. aureus
- Type: Human scFv
- Application: ELISA
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- Human Anti-WWP2 Recombinant Antibody; Fab Fragment (HPAB-0088-WJ-F(E)) (HPAB-0088-WJ-F(E))
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- Derivation: Hybridoma
- Species Reactivity: S. aureus
- Type: Human Fab
- Application: ELISA
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- Recombinant Human Anti-human WWP2 Antibody Fab Fragment (MHH-1054-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: RIA, IP, FuncS
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- Recombinant Human Anti-human WWP2 Antibody scFv Fragment (MHH-1054-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, Neut, FuncS
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- Recombinant Anti-human WWP2 Antibody Fab Fragment (MOB-1054-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: Neut, WB, FuncS
Compare
- Recombinant Anti-human WWP2 Antibody scFv Fragment (MOB-1054-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IF, FuncS
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with POU5F1, RBP1, EGR2 and SLC11A2 (By similarity). Interacts with SCNN1A, SCNN1B, SCNN1G, WBP1, WBP2 and ATN1. Interacts with ERBB4, NDFIP1 AND NDFIP2. Interacts with ARRDC4 (PubMed:23236378). Interacts (via WW domains) with ARRDC1 (via PPxY motifs); ubiquitinates ARRDC1 (PubMed:22315426, 21191027). Interacts (via WW domains) with ARRDC2 and ARRDC3 (PubMed:21191027). (Microbial infection) Interacts with adenovirus type 2 PIII.
Molecular function
Transferase
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