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PDGFB

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PDGFB is a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which function in a wide range of developmental processes. Mutations in PDGFB are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor.

Species Reactivity:
Human
Type:
Antibody
Derivation:
Human
Species Reactivity:
Human
Type:
Fab
Application:
WB, ELISA, FuncS
Derivation:
Phage display library screening
Species Reactivity:
Mouse, Rat, Human, Predicted to work with: Sheep
Type:
IgG
Application:
WB, IHC-P
Species Reactivity:
Human
Type:
Human IgG
Application:
ELISA, FC, IF, BL
Species Reactivity:
Human, Rat
Type:
Rat IgG2b, κ
Application:
ELISA, BL
Species Reactivity:
Human, Rat
Type:
Rat IgG2b, λ
Application:
ELISA, BL
Species Reactivity:
Human, Rat
Type:
Rat IgG2b, κ
Application:
ELISA, BL
Derivation:
Humanized
Species Reactivity:
Human, Rat
Type:
Humanized IgG
Application:
ELISA, BL
Derivation:
Humanized
Species Reactivity:
Human, Rat
Type:
Humanized IgG
Application:
ELISA, BL
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, FC, IF, BL
Species Reactivity:
Human, Rat
Type:
Rat scFv
Application:
ELISA, BL
Species Reactivity:
Human, Rat
Type:
Rat scFv
Application:
ELISA, BL
Species Reactivity:
Human, Rat
Type:
Rat scFv
Application:
ELISA, BL
Derivation:
Humanized
Species Reactivity:
Human, Rat
Type:
Humanized scFv
Application:
ELISA, BL
Derivation:
Humanized
Species Reactivity:
Human, Rat
Type:
Humanized scFv
Application:
ELISA, BL
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, FC, IF, BL
Species Reactivity:
Human, Rat
Type:
Rat Fab
Application:
ELISA, BL
Species Reactivity:
Human, Rat
Type:
Rat Fab
Application:
ELISA, BL
Species Reactivity:
Human, Rat
Type:
Rat Fab
Application:
ELISA, BL
Derivation:
Humanized
Species Reactivity:
Human, Rat
Type:
Humanized Fab
Application:
ELISA, BL
Derivation:
Humanized
Species Reactivity:
Human, Rat
Type:
Humanized Fab
Application:
ELISA, BL
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