Recombinant Anti-human ABL Intrabody [+36 GFP]
CAT#: IAB-B048(G)
Recombinant anti-ABL intrabody in fusion with +36GFP works within cells to bind human ABL, expressed in CHO cells. Inhibition of the BCR/ABL protein tyrosine kinase activity by the intrabody blocked BCR/ABL signal transduction pathway,reversed the effect of BCR/ABL on cell growth and apoptosis.












Specifications
- Immunogen
- human ABL proto-oncogene 1, non-receptor tyrosine kinase
- Host Species
- mouse
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Formats of immunological tests: Coimmunopricipation; Functional studies
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Target
- Alternative Names
- Abelson murine leukemia viral oncogene homolog 2; Abelson related gene protein; Abelson tyrosine-protein kinase 2;
Abelson-related gene protein; ABL2; ABL2_HUMAN; ABLL; ARG; Tyrosine kinase ARG; Tyrosine protein kinase ABL2; Tyrosine-protein kinase A
- Gene ID
- 25
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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See other products for "ABL"
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CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B048(A) | Recombinant Anti-human ABL Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
IAB-B048(T) | Recombinant Anti-human ABL Intrabody [Tat] | ELISA, IF, Neut, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
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VS-0625-FY314 | Mouse Anti-ABL Recombinant Antibody (clone 2506W0209) | ELISA | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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