What is the typical concentration range for using clone Inotuzumab in immunohistochemistry?

For immunohistochemistry applications, the typical working concentration ranges from 1-10 µg/mL, depending on the specific protocol and sample type.

Can this antibody be used in in vivo studies, such as animal models?

Yes, clone Inotuzumab has been successfully used in various in vivo studies, particularly in mouse models, to study B-cell depletion and related phenomena.

Is there any lot-to-lot variability in antibody performance?

The production of clone Inotuzumab is highly standardized to minimize lot-to-lot variability, ensuring consistent performance in research applications.

Human Anti-CD22 Recombinant Antibody (TAB-1725CL)

CAT#: TAB-1725CL

This product is a recombinant human antibody that recognizes CD22. The antibody was purified by affinity chromatography. It can be used for Block, Cyt, ELISA, FuncS and other applications.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_A_7_8.jpg

Normal Tissue Figure 2 Spleen

Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2418/6101_B_7_4.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012124-CD22

❮

❯

Specifications

Host Species
Human

Derivation
Humanized

Type
Humanized IgG

Specificity
Human

Species Reactivity
Human

Applications
Block, Cyt, ELISA, FuncS

Related Disease
B cell malignancies, graft-versus-host disease (GVHD), humoral rejection, and post-transplantation lymphoproliferative disorder and autoimmune disease

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Gene ID
933

UniProt ID
P20273

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for TAB-1725CL. Click the button above to contact us or submit your feedback about this product.

Breast cancer biomarkers at key points during disease progression

Excellent in Animal Models

We have used this antibody in mouse models for B-cell depletion studies. It has shown excellent efficacy and specificity in targeting CD22, aiding our research significantly.

Optimal Concentration Range

The recommended concentration range for immunohistochemistry is spot on. We achieved optimal staining results with 5 µg/mL, providing clear and distinct labeling of CD22.

High Affinity Binding

The binding affinity of clone Inotuzumab to CD22 is impressive. It outperforms other antibodies we have tested, making it our go-to choice for sensitive assays.

Q&As

What is the typical concentration range for using clone Inotuzumab in immunohistochemistry?

A: For immunohistochemistry applications, the typical working concentration ranges from 1-10 µg/mL, depending on the specific protocol and sample type.
Can this antibody be used in in vivo studies, such as animal models?

A: Yes, clone Inotuzumab has been successfully used in various in vivo studies, particularly in mouse models, to study B-cell depletion and related phenomena.
Is there any lot-to-lot variability in antibody performance?

A: The production of clone Inotuzumab is highly standardized to minimize lot-to-lot variability, ensuring consistent performance in research applications.

View the frequently asked questions answered by Creative Biolabs Support.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-1725CL.pdf

MSDS

MSDS - TAB-1725CL.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "CD22"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1248z	Mouse IgG1, kappa Anti-CD22 Recombinant Antibody (MOB-1248z)	IF, FC	Mouse IgG1, κ

CAT	Product Name	Application	Type
MOB-1248z-F(E)	Recombinant Anti-Human CD22 Antibody Fab Fragment	IP, RIA, FuncS	Fab

CAT	Product Name	Application	Type
MOB-1248z-S(P)	Recombinant Anti-Human CD22 Antibody scFv Fragment	ELISA, WB, IF, FuncS	scFv

CAT	Product Name	Application	Type
TAB-176	Anti-Human CD22 Recombinant Antibody (TAB-176)	IF, IP, Neut, FuncS, ELISA, FC, ICC	IgG1

CAT	Product Name	Application	Type
TAB-183-F(E)	Anti-Human CD22 Recombinant Antibody (TAB-183-F(E))	FuncS, IF, Neut, ELISA, FC, IP, ICC	Fv - disulfide stabilized

CAT	Product Name	Application	Type
TAB-198	Humanized Anti-CD22 Recombinant Antibody (clone Inotuzumab)	ELISA, FC, IP, FuncS, IF, Neut, ICC	Humanized (from mouse) IgG4, κ

CAT	Product Name	Application	Type
TAB-047-F(E)	Anti-Human CD22 Recombinant Antibody Fab Fragment(Bectumomab)	ELISA, FC, IP, FuncS, IF, Neut, WB	Fab' - G2a - kappa

CAT	Product Name	Application	Type
TAB-899	Humanized Anti-CD22 Recombinant Antibody (clone Pinatuzumab)	FC, IP, ELISA, Neut, FuncS, IF, ICC	Humanized (from mouse) IgG1, κ

CAT	Product Name	Application	Type
AGTO-G077E	Anti-CD22 immunotoxin RFB4 (IgG)-PE	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
AGTO-G077D	Anti-CD22 immunotoxin RFB4 (IgG)-DT	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
AGTO-G077G	Anti-CD22 immunotoxin RFB4 (IgG)-Gel	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
AGTO-G077R	Anti-CD22 immunotoxin RFB4 (IgG)-RTA	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
AGTO-G077S	Anti-CD22 immunotoxin RFB4 (IgG)-Sap	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
TAB-0196CL	Anti-Human CD22 Recombinant Antibody (hLL2)	Inhib, Cyt, FC, WB

CAT	Product Name	Application	Type
TAB-0197CL	Anti-Human CD22 Recombinant Antibody (hLL2-Cys)	ELISA, In vivo

CAT	Product Name	Application	Type
TAB-1714CL	Mouse Anti-CD22 Recombinant Antibody (TAB-1714CL)	ELISA, WB	Mouse IgG

CAT	Product Name	Application	Type
TAB-1715CL	Human Anti-CD22 Recombinant Antibody (TAB-1715CL)	Cyt, FuncS	Fully human antibody

CAT	Product Name	Application	Type
TAB-1716CL	Human Anti-CD22 Recombinant Antibody (TAB-1716CL)	Cyt, FuncS	Fully human antibody

CAT	Product Name	Application	Type
TAB-1717CL	Human Anti-CD22 Recombinant Antibody (TAB-1717CL)	Cyt, FuncS	Fully human antibody

CAT	Product Name	Application	Type
TAB-1724CL	Human Anti-CD22 Recombinant Antibody (TAB-1724CL)	Inhib	Chimeric (mouse/human) IgG1, κ

CAT	Product Name	Application	Type
TAB-1728CL	Anti-Human CD22 Recombinant Antibody (RFB4)	IF, FC

CAT	Product Name	Application	Type
TAB-1729CL	Human Anti-CD22 Recombinant Antibody (TAB-1729CL)	IF, FC	Humanized IgG

CAT	Product Name	Application	Type
TAB-1714CL-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1714CL-S(P))	ELISA, WB	Mouse scFv

CAT	Product Name	Application	Type
TAB-1724CL-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1724CL-S(P))	Inhib	Mouse scFv

CAT	Product Name	Application	Type
TAB-1725CL-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1725CL-S(P))	Block, Cyt, ELISA, FuncS	Humanized scFv

CAT	Product Name	Application	Type
TAB-1724CL-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1724CL-F(E))	Inhib	Chimeric (mouse/human) Fab

CAT	Product Name	Application	Type
TAB-001LC	Human Anti-CD22 Recombinant Antibody (TAB-001LC)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
TAB-001LC-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-001LC-S(P))	ELISA	Mouse scFv

CAT	Product Name	Application	Type
Gly-001LC	Recombinant Anti-Human CD22 Antibody (Fab glycosylation)	ELISA, FC	Mouse antibody

CAT	Product Name	Application	Type
Gly-111LC	Recombinant Anti-Human CD22 Antibody (Fc glycosylation)	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
MOB-0349MZ	Mouse Anti-CD22 Recombinant Antibody (clone 5LB129)	ELISA	Mouse IgG1

CAT	Product Name	Application	Type
NEUT-315CQ	Rat Anti-CD22 Recombinant Antibody (clone 2D6)	Block	Rat IgG1, κ

CAT	Product Name	Application	Type
MOR-0545	Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB)	IP, WB	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0195-LSX	Human Anti-CD22 Recombinant Antibody (HPAB-0195-LSX)	Apop, Cyt, FC, WB, Inhib, FuncS, IF, ELISA	Human IgG

CAT	Product Name	Application	Type
HPAB-0196-LSX	Mouse Anti-CD22 Recombinant Antibody (HPAB-0196-LSX)	ELISA, FC, IP, RIA	Mouse IgG

CAT	Product Name	Application	Type
HPAB-0197-LSX	Human Anti-CD22 Recombinant Antibody (HPAB-0197-LSX)	ELISA, FC, FuncS	Human IgG

CAT	Product Name	Application	Type
HPAB-0194-LSX-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0194-LSX-S(P))	ELISA	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0195-LSX-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0195-LSX-S(P))	ELISA	Human scFv

CAT	Product Name	Application	Type
HPAB-0196-LSX-S(P)	Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0196-LSX-S(P))	ELISA	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0197-LSX-S(P)	Human Anti-CD22 Recombinant Antibody; scFv Fragment (HPAB-0197-LSX-S(P))	ELISA	Human scFv

CAT	Product Name	Application	Type
HPAB-0194-LSX-F(E)	Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0194-LSX-F(E))	ELISA	Mouse Fab

CAT	Product Name	Application	Type
HPAB-0195-LSX-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0195-LSX-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
HPAB-0196-LSX-F(E)	Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0196-LSX-F(E))	ELISA	Mouse Fab

CAT	Product Name	Application	Type
HPAB-0197-LSX-F(E)	Human Anti-CD22 Recombinant Antibody; Fab Fragment (HPAB-0197-LSX-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
AFC-TAB-176	Afuco™ Anti-CD22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-176)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-198	Afuco™ Anti-CD22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-198)	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0424-XY50	AbPlus™ Anti-CD22 Magnetic Beads (DM13)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0724-YC918	AbPlus™ Anti-Cd22 Magnetic Beads (VS-0724-YC918)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0225-XY24	CytoStream™ Mouse Anti-CD22 Recombinant Antibody (VS-0225-XY24)	FC	Mouse IgG1, kappa

CAT	Product Name	Application	Type
VS-0325-XY357	Anti-CD22 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0425-FY82	Human Anti-CD22 (clone Inotuzumab) scFv-Fc Chimera	ELISA	Human IgG4, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC225	Recombinant Anti-CD22 Vesicular Antibody, EV Displayed (VS-0425-YC225)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-YC201	Recombinant Anti-CD22 (Epitope A x Epitope B) Biparatopic Antibody, Tandem scFv	ELISA, FC, ICC, IF, IP, Neut	Tandem scFv

CAT	Product Name	Application	Type
VS-0525-XY1143	Anti-Human CD22 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0825-YC43	SmartAb™ Recombinant Anti-CD22 pH-dependent Antibody (Clone Inotuzumab)	ELISA, FC, IP IF, Neut, ICC	Human IgG4 kappa

CAT	Product Name	Application	Type
VS-1025-YC100	Anti-CD22 Antibody Prodrug, Protease Activated (VS-1025-YC100)	ISZ, Cyt, FuncS

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 3 Anti-Human IL17RA Antibody (TAB-134) in DB

Human Anti-IL17RA Recombinant Antibody (TAB-134) (CAT# TAB-134)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 2 Anti-EGFR Recombinant Antibody (TAB-710) in ELISA

Anti-EGFR Recombinant Antibody (Nimotuzumab) (CAT# TAB-710)
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC

Figure 2 Anti-IL22 Recombinant Antibody (TAB-748) in HPLC

Anti-IL22 Recombinant Antibody (TAB-748) (CAT# TAB-748)
Application: WB, IP, IF, FuncS, FC, Neut, ELISA

Figure 2 Anti-EGFR Recombinant Antibody (TAB-753) in HPLC

Anti-EGFR Recombinant Antibody (Imgatuzumab) (CAT# TAB-753)
Application: Neut, ELISA, IF, IP, FuncS, FC, WB

Figure 2 Anti-Human CD23 Recombinant Antibody (Gomiliximab) (TAB-231) in ELISA

Anti-Human CD23 Recombinant Antibody (Gomiliximab) (CAT# TAB-231)
Application: WB, Neut, ELISA, IF, IP, FuncS, FC

Figure 2 Recombinant Human Anti-IAV HA1 chain Antibody (C05) (PABL-223) in SEC-HPLC

Recombinant Human Anti-IAV HA1 chain Antibody (C05) (CAT# PABL-223)
Application: WB, ELISA, FuncS

Figure 3 Mouse Anti-VEGF Recombinant Antibody (PABW-130) in ELISA

Mouse Anti-VEGF Recombinant Antibody (clone A4.6.1) (CAT# PABW-130)
Application: Neut, ELISA, Inhib, ICC, WB

Figure 2 Anti-Human CD19 Recombinant Antibody Fab Fragment [TAB-1611CL-F(E)] in HPLC

Mouse Anti-CD19 Recombinant Antibody; Fab Fragment (TAB-1611CL-F(E)) (CAT# TAB-1611CL-F(E))
Application: Depletion, FuncS

Figure 1 Anti-Human TfR Recombinant Antibody (TAB-628CT) in SDS-PAGE

Anti-Human TfR Recombinant Antibody (3GH7 ) (CAT# TAB-628CT)
Application: WB

Figure 2 Anti-Human SLAMF6 Antibody (TAB-605MZ) in ELISA

Human Anti-SLAMF6 Recombinant Antibody (TAB-605MZ) (CAT# TAB-605MZ)
Application: Cyt, FuncS

Figure 8 Anti-Influenza A Virus Hemagglutinin H3 HA Recombinant Antibody (MRO-280LC) in DB

Mouse Anti-Influenza A Virus Hemagglutinin H3 HA Recombinant Antibody (MRO-280LC) (CAT# MRO-280LC)
Application: WB, ELISA, IF

Figure 2 Anti-Human SNCA Antibody (TAB-0748CLV) in ELISA

Mouse Anti-SNCA Recombinant Antibody (TAB-0748CLV) (CAT# TAB-0748CLV)
Application: ELISA, DB, WB

Figure 2 Recombinant Rat Anti-NGF Antibody (PABX-146) in SDS-PAGE

Recombinant Rat Anti-NGF Antibody (αD11) (CAT# PABX-146)
Application: Neut, FC, FuncS

Figure 2 Anti-Human F9 Antibody (EPAF-0574CQ) in HPLC

Recombinant Human Anti-Human F9 Antibody (10C12) (CAT# EPAF-0574CQ)
Application: ELISA

Figure 5 Recombinant Mouse Anti-MARV GP Antibody (EPAF-0808CQ) in Dot Blot

Recombinant Mouse Anti-MARV GP Antibody (7E10) (CAT# EPAF-0808CQ)
Application: WB, IP

Figure 5 Mouse Anti-FCRL5 Recombinant Antibody (MOB-056CQ) in DB

Mouse Anti-FCRL5 Recombinant Antibody (MOB-056CQ) (CAT# MOB-056CQ)
Application: ELISA, FC, FuncS

Figure 2 Mouse Anti-Histone Recombinant Antibody (FAMAB-0160YC) in HPLC

Mouse Anti-Histone Recombinant Antibody (clone LG2-1) (CAT# FAMAB-0160YC)
Application: IF

Figure 4 Mouse Anti-EGFR Recombinant Antibody (HPAB-0727-CN) in WB

Mouse Anti-EGFR Recombinant Antibody (clone EGFR) (CAT# HPAB-0727-CN)
Application: ELISA, FC, IHC, Neut

Figure 2 Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0693-YC) in HPLC

Mouse Anti-MRC2 Recombinant Antibody (HPAB-M0693-YC) (CAT# HPAB-M0693-YC)
Application: WB, FuncS

Figure 2 Mouse Anti-His Tag Recombinant Antibody; Fab Fragment (HPAB-0328-WJ-F(E)) in ELISA

Mouse Anti-His Tag Recombinant Antibody; Fab Fragment (HPAB-0328-WJ-F(E)) (CAT# HPAB-0328-WJ-F(E))
Application: ELISA, WB

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.