Human Anti-CD22 Recombinant Antibody (TAB-1725CL)

CAT#: TAB-1725CL

This product is a recombinant human antibody that recognizes CD22. The antibody was purified by affinity chromatography. It can be used for Block, Cyt, ELISA, FuncS and other applications.

Gene Expression
Figure 1 Lymph node Figure 2 Spleen Figure 3 RNA cell line category: Cell line enhanced (Daudi, REH, U-698, WM-115)

Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized IgG
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Applications
  • Block, Cyt, ELISA, FuncS
  • Related Disease
  • B cell malignancies, graft-versus-host disease (GVHD), humoral rejection, and post-transplantation lymphoproliferative disorder and autoimmune disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
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Breast cancer biomarkers at key points during disease progression
Excellent in Animal Models
We have used this antibody in mouse models for B-cell depletion studies. It has shown excellent efficacy and specificity in targeting CD22, aiding our research significantly.
Breast cancer biomarkers at key points during disease progression
Optimal Concentration Range
The recommended concentration range for immunohistochemistry is spot on. We achieved optimal staining results with 5 µg/mL, providing clear and distinct labeling of CD22.
Breast cancer biomarkers at key points during disease progression
High Affinity Binding
The binding affinity of clone Inotuzumab to CD22 is impressive. It outperforms other antibodies we have tested, making it our go-to choice for sensitive assays.

Q&As

  1. What is the typical concentration range for using clone Inotuzumab in immunohistochemistry?

    A: For immunohistochemistry applications, the typical working concentration ranges from 1-10 µg/mL, depending on the specific protocol and sample type.

  2. Can this antibody be used in in vivo studies, such as animal models?

    A: Yes, clone Inotuzumab has been successfully used in various in vivo studies, particularly in mouse models, to study B-cell depletion and related phenomena.

  3. Is there any lot-to-lot variability in antibody performance?

    A: The production of clone Inotuzumab is highly standardized to minimize lot-to-lot variability, ensuring consistent performance in research applications.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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