Anti-Human CD22 Recombinant Antibody (19A3) (CAT#: TAB-1716CL)
This monoclonal antibody that specifically binds to CD22 with high affinity can be used for detecting CD22, as well as for treating various cancers and inflammatory and autoimmune disorders.
Specific Inquiry
Cyt
Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.
Cyt
Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.
FuncS
Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.
FuncS
Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.
Specifications
- Immunogen
- The extracellular domain of human CD22 and the full-length CD22 protein expressed on CHO cells
- Host Species
- Human
- Derivation
- Human
- Type
- Fully human antibody
- Specificity
- Human
- Clone
- 19A3
- Applications
- Cyt, FuncS
- Related Disease
- Cancers and inflammatory and autoimmune disorders
Applications
- Application Notes
- This antibody has been reported for use in Cytotoxicity, Functional Assay.
Target
- Alternative Names
- CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2
- Gene ID
- 933
- UniProt ID
- P20273
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fc Glycosylation
Blocking Antibody
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Fab Fragment Antibody
Recombinant Antibody
scFv Fragment Antibody
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-176 | Anti-Human CD22 Recombinant Antibody (Epratuzumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 |
| TAB-899 | Humanized Anti-CD22 Recombinant Antibody (clone Pinatuzumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | Humanized (from mouse) IgG1, κ |
| TAB-1725CL | Human Anti-CD22 Recombinant Antibody (TAB-1725CL) | Block, Cyt, ELISA, FuncS | Humanized IgG |
| TAB-1729CL | Human Anti-CD22 Recombinant Antibody (TAB-1729CL) | IF, FC | Humanized IgG |
| TAB-002LC | Anti-Human CD22 Recombinant Antibody (VM1000) | FC, ELISA, SPR, FuncS | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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