Anti-Human CD22 Recombinant Antibody (12C5) (CAT#: TAB-1715CL)

This monoclonal antibody that specifically binds to CD22 with high affinity can be used for detecting CD22, as well as for treating various cancers and inflammatory and autoimmune disorders.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Tested Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Cyt

Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.

Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.

Cyt

Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.

Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.

FuncS

Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.

Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.

FuncS

Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.

Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.


Specifications

  • Immunogen
  • The extracellular domain of human CD22 and the full-length CD22 protein expressed on CHO cells
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Fully human antibody
  • Specificity
  • Human
  • Clone
  • 12C5
  • Applications
  • Cyt, FuncS
  • Related Disease
  • Cancers and inflammatory and autoimmune disorders

Applications

  • Application Notes
  • This antibody has been reported for use in Cytotoxicity, Functional Assay.

Target

  • Alternative Names
  • CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 12C5"

See other products for "CD22"

Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products Humanized Antibody Products Immunotoxin Products Human Antibody Products Chimeric Antibody Products Mouse Antibody Products Fab Glycosylation Antibody Products Fc Glycosylation Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products ScFv Antibody Products Antibody Magnetic Beads

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for TAB-1715CL. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare