Anti-Human CD22 Recombinant Antibody (12C5) (CAT#: TAB-1715CL)

This monoclonal antibody that specifically binds to CD22 with high affinity can be used for detecting CD22, as well as for treating various cancers and inflammatory and autoimmune disorders.


Specific Inquiry
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  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Tested Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Cyt

Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.

Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.

Cyt

Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.

Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.

FuncS

Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.

Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.

FuncS

Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.

Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.


Specifications

  • Immunogen
  • The extracellular domain of human CD22 and the full-length CD22 protein expressed on CHO cells
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Fully human antibody
  • Specificity
  • Human
  • Clone
  • 12C5
  • Applications
  • Cyt, FuncS
  • Related Disease
  • Cancers and inflammatory and autoimmune disorders

Applications

  • Application Notes
  • This antibody has been reported for use in Cytotoxicity, Functional Assay.

Target

  • Alternative Names
  • CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 12C5"

See other products for "CD22"

Mouse Antibody

Immunotoxin

CAT Product Name Application Type
AGTO-G077E Anti-CD22 immunotoxin RFB4 (IgG)-PE Cytotoxicity assay, Function study
AGTO-G077D Anti-CD22 immunotoxin RFB4 (IgG)-DT Cytotoxicity assay, Function study
AGTO-G077G Anti-CD22 immunotoxin RFB4 (IgG)-Gel Cytotoxicity assay, Function study
AGTO-G077R Anti-CD22 immunotoxin RFB4 (IgG)-RTA Cytotoxicity assay, Function study
AGTO-G077S Anti-CD22 immunotoxin RFB4 (IgG)-Sap Cytotoxicity assay, Function study

Human Antibody

Fab Glycosylation

CAT Product Name Application Type
Gly-001LC Recombinant Anti-Human CD22 Antibody (Fab glycosylation) ELISA, FC Mouse antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-111LC Recombinant Anti-Human CD22 Antibody (Fc glycosylation) ELISA Chimeric antibody (mouse/human)

Blocking Antibody

CAT Product Name Application Type
NEUT-315CQ Rat Anti-CD22 Recombinant Antibody (clone 2D6) Block Rat IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0545 Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB) IP, WB Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-176 Afuco™ Anti-CD22 ADCC Recombinant Antibody (Epratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-198 Afuco™ Anti-CD22 ADCC Recombinant Antibody (Inotuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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