Recombinant Human Anti-HCV E1 Antibody (PABL-117) (CAT#: PABL-117)
Recombinant Human Antibody is capable of binding to HCV E1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HCV E1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HCV E1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This neutralizing antibody bound to a discontinuous epitope, but with a major component corresponding to E1 residues 314-324.
Specific Inquiry
Specifications
- Immunogen
- Hepatitis C virus E1 envelope protein
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native HCV E1
- Species Reactivity
- HCV
- Applications
- ELISA, Neut, FuncS
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The antibody was validated for ELISA and Neut. For details, refer to published data.
Target
- Alternative Names
- E1; HCV; envelope protein; hepatitis C virus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv Antibody Products
Fab Antibody Products
MHC Tetramer Products for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-117 | Recombinant Human Anti-HCV E1 Antibody scFv Fragment (PSBL-117) | Neut, FuncS | scFv |
Customer Reviews and Q&As
Customer Review
Q&As
Extremely Specific and Reliable
I've used this antibody for ELISA assays to detect HCV E1 protein in serum samples. The specificity and sensitivity are top-notch, with no background noise.
Enhanced Understanding of HCV Entry
This antibody has significantly enhanced my research on HCV entry mechanisms. Its specificity for the E1 glycoprotein is exceptional.
Crucial for Studying HCV Evasion
This antibody has been crucial in studying how HCV evades immune responses, particularly involving the E1 glycoprotein.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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