Anti-Human ITGA4+ITGB7 Recombinant Antibody (TAB-H75) (CAT#: TAB-H75)
Recombinant Humanized (from mouse) antibody to Human ITGA4+ITGB7. It is a monoclonal antibody for the treatment of ulcerative colitis and Crohn's disease.It binds to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1). Blocking the α4β7 integrin results in gut-selective anti-inflammatory activity. It is marketed under the trade name vedolizumab.
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ELISA
Figure 1 Anti-alpha 4 beta 7 Antibody (TAB-H75) in ELISA
ELISA analysis of TAB-H75 was performed by coating with Human alpha 4 beta 7 Protein.
DB
Figure 2 Anti-alpha 4 beta 7 Antibody (TAB-H75) in Dot Blot
Dot Blot analysis of TAB-H75 was performed by coating with Human alpha 4 beta 7 Protein.
Specifications
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Specificity
- ITGA4_ITGB7(integrin alpha4 (CD49d)_beta7, integrin alpha4_beta7, integrin α4β7, lymphocyte Peyer s patch adhesion molecule 1, LPAM-1) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF, WB
- MW
- 146.8 kDa
- Related Disease
- Ulcerative colitis (UC)
Product Property
- Purity
- Purity >95% by SDS-PAGE.
Applications
- Application Notes
- The ITGA4+ITGB7 antibody has been reported in applications of FC, IF, Inhib, Agonist, H&E staining, IHC.
Target
- Alternative Names
- vedolizumab;vedolizumab;943609-66-3;MLN0002;MLN02;LDP02;ITGA4;ITGB7;Integrin α4β7;CD49d/β7
Related Resources
Please refer to Vedolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Vedolizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Human Antibody Products
ADCC Enhanced Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H02 | Anti-Human ITGA4+ITGB7 Recombinant Antibody (TAB-H02) | IP, IF, FuncS, FC, Neut, ELISA, WB | IgG2 - kappa |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-H75, RRID: AB_3112046)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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