Recombinant Mouse Antibody (GD01 ) is capable of binding to JUNV GP1, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 Competition ELISA: GD01 or 17b competitor IgG was added at increasing concentrations to plates coated with JUNV GP1, and the indicated AHF survivor IgG were added at fixed concentrations. Survivor IgG that bound to the plate was detected using a secondary anti-human HRP-conjugated antibody.
Mahmutovic, S., Clark, L., Levis, S. C., Briggiler, A. M., Enria, D. A., Harrison, S. C., & Abraham, J. (2015). Molecular basis for antibody-mediated neutralization of New World hemorrhagic fever mammarenaviruses. Cell host & microbe, 18(6), 705-713.
Figure 2 ELISA analysis of nAb OD01 titrated against immobilized arenavirus GP1 glycoproteins. Wells were coated with JUNV GP1, MACV GP1, or LCMV GP1 (negative control).
Zeltina, A., Krumm, S. A., Sahin, M., Struwe, W. B., Harlos, K., Nunberg, J. H.,... & Bowden, T. A. (2017). Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization. Proceedings of the National Academy of Sciences, 114(27), 7031-7036.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-253 | Recombinant Mouse Anti-JUNV GP1 Antibody scFv Fragment (GD01 ) | ELISA, FuncS | scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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