Anti-NCT Intrabody [+36GFP] (IAB-B045(G))
Recombinant anti-NCT intrabody in fusion with +36GFP works within cells to suppressed the NCT activity, expressed in CHO cells. Nicastrin (NCT), a single-pass membrane glycoprotein that harbors a large extracellular domain, is an essential component of the γ-secretase complex.
Specifications
- Immunogen
- human Nicastrin
- Host
- mouse
- Type
- scFv-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Antibody assay: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies
Target
- Alternative Names
- NCT; Nicastrin; Anterior pharynx defective 2; APH2; ATAG1874; KIAA0253; NCSTN; NICA_HUMAN
For lab research use only, not for diagnostic, therapeutic or any in vivo human use.
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