This antibody reacting with all strains of P. acnes serotype 1 can be used for detecting P. acnes.
Figure 1 Immunohistochemistry of prostate glands with the PAL antibody.
The antibody reacted with small round bodies (arrows) in some non-cancerous glandular epithelial cells.
Intracellular Propionibacterium acnes Infection in Glandular Epithelium and Stromal Macrophages of the Prostate with or without Cancer
Figure 2 Immunohistochemistry of prostate tissues with the PAL antibody.
Positive signals by the antibody were more frequent in glands with epithelial hyperplasia (A, B) than in normal or atrophic glands (C, D). In the prostatic stroma, positive signals were found in macrophage-like cells accompanied by mononuclear inflammatory cells (E, F). A few positive signals were infrequently found in some cancer cells (G, H). Higher magnification of the area indicated by the arrow is shown in the inset of each figure.
Intracellular Propionibacterium acnes Infection in Glandular Epithelium and Stromal Macrophages of the Prostate with or without Cancer
Figure 3 Characterization of P. acnes-positive cells and differentiation between P. acnes-positive signals and lipofuscin in prostate.
Immunofluorescence double-staining of the P. acnes-positive cells in prostate tissues (A–C). Green signal (FITC): PAL antibody; red signals (TRITC): anti-cytokeratin antibody (A), anti-CD68 antibody (B), and anti-fascin antibody (C).
Intracellular Propionibacterium acnes Infection in Glandular Epithelium and Stromal Macrophages of the Prostate with or without Cancer
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MRO-167MZ-S(P) | Anti-P. acnes serotype 1 Recombinant Antibody scFv Fragment (PAL) (MRO-167MZ-S(P)) | WB, IHC | |
MRO-167MZ-F(E) | Anti-P. acnes serotype 1 Recombinant Antibody Fab Fragment (PAL) (MRO-167MZ-F(E)) | WB, IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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