Anti-Human RSV-F Recombinant Antibody (D25) (CAT#: TAB-360CT)
Recombinant monoclonal antibody specifically binds to the fusion (F) protein of Respiratory Syncytial Virus (RSV).
Specific Inquiry
Neut
Figure 1 RSV neutralization by antibodies.
RSV neutralization, F glycoprotein recognition, and crystal structure of human antibody D25 in complex with the prefusion RSV F trimer.
McLellan, J. S., Chen, M., Leung, S., Graepel, K. W., Du, X., Yang, Y., ... & Kumar, A. (2013). Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science, 340(6136), 1113-1117.
Inhib
Figure 2 Fusion inhibition activity for antibodies targeting antigenic site Ø and F-specific antibodies targeting other antigenic sites.
For the attachment-inhibition assay, heparin was used as a positive control. Data are representative of multiple independent experiments.
McLellan, J. S., Chen, M., Leung, S., Graepel, K. W., Du, X., Yang, Y., ... & Kumar, A. (2013). Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science, 340(6136), 1113-1117.
Specifications
- Immunogen
- RSV F protein
- Host Species
- Human
- Derivation
- Human phage display library
- Type
- Human antibody
- Specificity
- RSV
- Species Reactivity
- RSV
- Clone
- D25
- Applications
- Neut, Inhib
- Related Disease
- RSV infection
Applications
- Application Notes
- This antibody has been reported for use in Neutralization and Inhibition Assay.
Target
- Alternative Names
- RSV-F; Respiratory Syncytial Virus F protein; RSV F; anti-RSV-F
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-359CT | Human Anti-RSV-F Recombinant Antibody (TAB-359CT) | ELISA, WB, Neut | Human IgG |
| TAB-359CT-S(P) | Human Anti-RSV-F Recombinant Antibody; scFv Fragment (TAB-359CT-S(P)) | ELISA, WB, Neut | Human scFv |
| TAB-360CT-S(P) | Anti-Human RSV-F Recombinant Antibody scFv Fragment (D25) | ELISA, WB, BL | Human antibody |
| TAB-359CT-F(E) | Human Anti-RSV-F Recombinant Antibody; Fab Fragment (TAB-359CT-F(E)) | ELISA, WB, Neut | Human Fab |
| TAB-360CT-F(E) | Anti-Human RSV-F Recombinant Antibody Fab Fragment (D25) | ELISA, WB, BL | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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