Afuco™ Anti-Human SLC2A8 ADCC Recombinant Antibody (VB1-050), ADCC Enhanced (CAT#: AFC-551CL)
Anti-SLC2A8 ADCC Enhanced Antibody (VB1-050) is an ADCC enhanced antibody produced by our Afuco™ platform. VB1-050 is an IgG MAb generated from pooled lymphocytes of cancer patient samples, using standard hybridoma techniques. This antibody demonstrates preferential binding to a host of tumor cell lines, including breast, liver, prostate and colon, with limited normal tissue reactivity. Further research is ongoing to assess the potential clinical exploitation of VB1-050/Glut-8.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/1030_C8_3_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/1030_C8_3_selected.jpg
Figure 2 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong nuclear and cytoplasmic positivity in cells of seminiferus ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_5_6_selected.jpg
(Immunohistochemical staining of human testis shows strong nuclear and cytoplasmic positivity in cells of seminiferus ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_5_6_selected.jpg
Figure 3 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_7_4.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_4_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11935/29605_A_4_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (CACO-2, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136856-SLC2A8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136856-SLC2A8
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- SLC2A8; solute carrier family 2 (facilitated glucose transporter), member 8; GLUT8; GLUTX1; solute carrier family 2, facilitated glucose transporter member 8; glucose transporter type 8; glucose transporter type X1
- Gene ID
- 29988
- UniProt ID
- Q5VVV9
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
Rabbit Monoclonal Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-386CQ | Human Anti-SLC2A8 Recombinant Antibody (TAB-386CQ) | Cyt, FC, WB | Human IgG |
| TAB-386CQ-S(P) | Human Anti-SLC2A8 Recombinant Antibody; scFv Fragment (TAB-386CQ-S(P)) | ELISA, WB | Human scFv |
| TAB-386CQ-F(E) | Human Anti-SLC2A8 Recombinant Antibody; Fab Fragment (TAB-386CQ-F(E)) | ELISA, WB | Human Fab |
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For Research Use Only. Not For Clinical Use.
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