DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
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CAT | Product Name | Application | Type |
---|---|---|---|
VS-0824-FY219 | Quick™ DM1 Antibody Labeling Kit (VS-0824-FY219) | Antibody Labeling |
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