PE-DQB1*06:02/Human HCRT (MNLPSTKVSWAAV) MHC Tetramer

CAT#: MHC-LC2067

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HCRT of peptide MNLPSTKVSWAAV covering 1-13 and DQB1*06:02 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 Low expression in endometrium 1 Figure 2 Cerebral cortex Figure 3 Kidney Figure 4 Testis

Specifications

  • Allele
  • DQB1*06:02
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • HCRT
  • Antigen Species
  • Human
  • Peptide
  • MNLPSTKVSWAAV
  • Range
  • 1-13
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]
  • Alternative Names
  • HCRT; Orexin precursor; OX; PPOX; NRCLP1
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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