PE-Mamu-B*003:01/Human FAU (RRFVNVVPTF) MHC Tetramer

CAT#: MHC-LC2998

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human FAU of peptide RRFVNVVPTF covering 40-49 and Mamu-B*003:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line PC-3 Figure 2 IHC staining of human colon Figure 3 IF staining of human cell line HEK 293 Figure 4 IF staining of human cell line U-2 OS Figure 5 Cerebral cortex Figure 6 Colon Figure 7 Liver Figure 8 Testis Figure 9 Breast Figure 10 RNA cell line category: Low cell line specificity

Specifications

  • Allele
  • Mamu-B*003:01
  • Class
  • Class I
  • MHC Species
  • Macaca
  • Antigen
  • FAU
  • Antigen Species
  • Human
  • Peptide
  • RRFVNVVPTF
  • Range
  • 40-49
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome and displays antimicrobial activity. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin.
  • Alternative Names
  • FAU; ubiquitin like and ribosomal protein S30 fusion; S30; FAU1; Fub1; Fubi; asr1; RPS30; MNSFbeta
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