A*02:01/Human Telomerase Reverse Transcriptase (hTRT) (GLLGASVLGL) MHC Pentamer
CAT#: MHC-YF739
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Telomerase Reverse Transcriptase (hTRT)-derived peptide of GLLGASVLGL sequence covering 674-683 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line LHCN-M2
Immunofluorescent staining of human cell line LHCN-M2 shows localization to nucleoplasm & nuclear speckles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54641/1782_B1_17_cr596b5f3cb51d0_selected.jpg
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Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- Telomerase Reverse Transcriptase (hTRT)
- Antigen Species
- Human
- Peptide
- GLLGASVLGL
- Range
- 674-683
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008]
- Alternative Names
- Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; Telomerase Catalytic Subunit; EC 2.7.7.49; HEST2; TCS1; EST2; TP2;
- Gene ID
- 7015
- UniProt ID
- O14746
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "TERT"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962 | Recombinant Anti-human TERT Antibody | WB, IHC, FuncS | IgG |
| MHH-962 | Recombinant Human Anti-human TERT Antibody | WB, Neut, FuncS | IgG |
| MOB-2004CT | Recombinant Mouse anti-Human TERT Monoclonal antibody (3D5) | FC, ICC, IF, IHC-P, IP, WB | |
| MRO-1480-CN | Rabbit Anti-TERT Recombinant Antibody (clone JF0586) | WB, FC | Rabbit IgG |
| ZG-0591U | Rabbit Anti-TERT Recombinant Antibody (clone 5C11) | ELISA, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962-F(E) | Recombinant Anti-human TERT Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
| MHH-962-F(E) | Recombinant Human Anti-human TERT Antibody Fab Fragment | WB, IHC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-962-S(P) | Recombinant Anti-human TERT Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-962-S(P) | Recombinant Human Anti-human TERT Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-050 | Recombinant Anti-human TERT VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B046(A) | Recombinant Anti-human TERT Intrabody [(D-Arg)9] | PCA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B046(G) | Recombinant Anti-human TERT Intrabody [+36 GFP] | WB, Neut, FuncS | scFv-(+36GFP) |
| IAB-B046(T) | Recombinant Anti-human TERT Intrabody [Tat] | WB, ICC, Neut, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0581MZ | Chicken Anti-TERT Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC792 | A*0201/Human hTERT (ILAKFLHWL) MHC Tetramer | FCM | |
| MHC-LC848 | PE-A*02:01/Human TERT (ILAKFLHTL) MHC Tetramer | FCM | |
| MHC-LC851 | PE-A*02:01/Human TERT (ILAKFLHEL) MHC Tetramer | FCM | |
| MHC-YF144 | H-2Kb/Mouse mTERT (VGRNFTNL) MHC Monomer | MHC Multimer | |
| MHC-YF160 | A*02:01/Human hTERT (ILAKFLHWL) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3533 | Rabbit Anti-TERT Recombinant Antibody (clone DS3533AB) | FC, ICC, IF, IHC-Fr, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC111 | Recombinant Anti-TERT Vesicular Antibody, EV Displayed (VS-0425-YC111) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7173 | Anti-TERT Immunohistochemistry Kit | IHC |
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