A*24:02/Human RNF43 (722Y) (NYQPVWLCL) MHC Pentamer
CAT#: MHC-YF707
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed RNF43 (722Y)-derived peptide of NYQPVWLCL sequence covering 721-729 and A*24:02 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong nuclear positivity in cells in tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8079/23746_A_7_5_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8079/23746_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8079/23746_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8079/23746_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8079/23746_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8079/23746_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (A549, CACO-2, Hep G2, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000108375-RNF43
❮
❯
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- RNF43 (722Y)
- Antigen Species
- Human
- Peptide
- NYQPVWLCL
- Range
- 721-729
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
- Alternative Names
- Ring Finger Protein 43; RING-Type E3 Ubiquitin Transferase RNF43; RING Finger Protein 43; E3 Ubiquitin-Protein Ligase RNF43; EC 2.3.2.27; RNF124; SSPCS; URCC;
- Gene ID
- 54894
- UniProt ID
- Q68DV7
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MHC-YF707. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "RNF43"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-327CT | Mouse Anti-RNF43 Recombinant Antibody (TAB-327CT) | WB, ELISA, FC, IHC, IP | Mouse IgG |
| TAB-327CT-S(P) | Mouse Anti-RNF43 Recombinant Antibody; scFv Fragment (TAB-327CT-S(P)) | WB, ELISA, FC, IHC, IP | Mouse scFv |
| TAB-327CT-F(E) | Mouse Anti-RNF43 Recombinant Antibody; Fab Fragment (TAB-327CT-F(E)) | WB, ELISA, FC, IHC, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-328CT | Humanized Anti-RNF43 Recombinant Antibody (TAB-328CT) | WB, ELISA, FC, IHC, IP | Humanized IgG1, κ |
| TAB-328CT-S(P) | Humanized Anti-RNF43 Recombinant Antibody; scFv Fragment (TAB-328CT-S(P)) | WB, ELISA, FC, IHC, IP | Humanized scFv |
| TAB-328CT-F(E) | Humanized Anti-RNF43 Recombinant Antibody; Fab Fragment (TAB-328CT-F(E)) | WB, ELISA, FC, IHC, IP | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1185 | PE-A*02:01/Human RNF43 (ALWPWLLMAT) MHC Tetramer | FCM, IHC | |
| MHC-CN1186 | APC-A*02:01/Human RNF43 (ALWPWLLMAT) MHC Tetramer | FCM, IHC | |
| MHC-CN1187 | FITC-A*02:01/Human RNF43 (ALWPWLLMAT) MHC Tetramer | FCM, IHC | |
| MHC-YF705 | A*02:01/Human RNF43 (ALWPWLLMA) MHC Pentamer | FCM | |
| MHC-YF706 | A*02:01/Human RNF43 (ALWPWLLMAT) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC181 | Recombinant Anti-RNF43 Vesicular Antibody, EV Displayed (VS-0425-YC181) | ELISA, FC, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, WB, BLI, SPR
Application: WB, Neut, FuncS
Application: FuncS, Inhib, IP, ELISA
-2.png)
Application: WB, ELISA, FC, IHC, IP
Application: Block, IP, IF, FC
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, WB, FC, IHC, IP
Application: ELISA, WB, Microarray, Block
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
