Human Anti-ABCB4 Recombinant Antibody (VS-0824-YJ43) (CAT#: VS-0824-YJ43)
CMA205 is a human IgG recognizing human ABCB4. It binds to the elbow helix of TMD2 (preceding TM7) as well as the linker between TM12 and the second nucleotide binding domain (NBD2). CMA206 is a human IgG recognizing human ABCB4. It binds to TM11 and NBD1.
| Sub Cat | Clone | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0824-YJ8 | CMA205 | ||||||
| VS-0824-YJ9 | CMA206 |
More Infomation
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, plasma membrane & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/if_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong positivity in bile canaliculi.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/124384_A_7_4_selected.jpg
(Immunohistochemical staining of human liver shows strong positivity in bile canaliculi.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49395/124384_A_7_4_selected.jpg
Figure 3 High expression in liver
(Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53288/166934_A_8_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53288/166934_A_8_4.jpg
Figure 4 RNA cell line category: Group enriched (SH-SY5Y, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005471-ABCB4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005471-ABCB4
Specifications
- Host Species
- Human
- Type
- Human IgG1 kappa
- Specificity
- Human ABCB4
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Inherited diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE or SEC-HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- GBD1; ICP3; MDR2; MDR3; PGY3; ABC21; MDR2/3; PFIC-3; phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4; P-glycoprotein 3; P-glycoprotein-3/multiple drug resistance-3; multidrug resistance protein 3; multiple drug resistance 3
- Gene ID
- 5244
- UniProt ID
- P15941
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ABCB4"
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0520MZ | Mouse Anti-ABCB4 Recombinant Antibody (clone Q4JJ-37) | FC, ICC, IHC-Fr, WB | Mouse IgG2b |
| VS3-QX3 | Mouse Anti-ABCB4 Recombinant Antibody (clone 1808CT346.21.23) | WB | Mouse IgG1, κ |
| VS3-FY2617 | Mouse Anti-ABCB4 Recombinant Antibody (VS3-FY2617) | WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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