Human Anti-CysLT Recombinant Antibody (clone LT5014/Hu10G4) (CAT#: PABC-497)
This product is a recombinant Human antibody that can recognize cysLT. 10G4 bound with highest affinity to LTC4, with a measured Kd value of less than 10 picomolar.
Specific Inquiry
ELISA
Figure 1 Binding affinity of anti-CysLT Hu10G4 antibody measured by ELISA.
Binding curves for antibody Hu10G4 interaction with LTC4 (red), LTD4 (blue), LTE4 (green), LTF4 (black), N-acetyl-LTE4 (orange), and LTB4 (light blue).
King, A. N., Fleming, J. K., Knapik, S. S., Visentin, B., Wojciak, J. M., & Huxford, T. (2017). High-affinity pan-specific monoclonal antibodies that target cysteinyl leukotrienes and show efficacy in an acute model of colitis. Journal of lipid research, 58(7), 1386-1398.
Specifications
- Immunogen
- LTE4 conjugated to protein carriers via disuccinimidyl homobifunctional cross-linking
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1, κ
- Clone
- LT5014/Hu10G4
- Applications
- ELISA
- Related Disease
- Inflammatory diseases and asthma
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- CysLT; Cysteinyl leukotriene
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone LT5014/Hu10G4"
See other products for "CysLT"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-498 | Mouse Anti-CysLT Recombinant Antibody (clone 10G4) | ELISA | Mouse IgG1, κ |
| PABC-499 | Mouse Anti-CysLT Recombinant Antibody (clone 14H3) | ELISA | Mouse IgG1, κ |
| PABC-500 | Mouse Anti-CysLT Recombinant Antibody (clone 2F9) | ELISA | Mouse IgG1, κ |
| PABC-502 | Mouse Anti-CysLT Recombinant Antibody (clone 9B12) | ELISA | Mouse IgG1, κ |
| PABC-503 | Mouse Anti-CysLT Recombinant Antibody (clone 2G9) | ELISA | Mouse IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-497 | Human Anti-CysLT Recombinant Antibody (clone LT5014/Hu10G4); Fab Fragment | ELISA | Humanized Fab |
| PFBC-498 | Mouse Anti-CysLT Recombinant Antibody (clone 10G4); Fab Fragment | ELISA | Mouse Fab |
| PFBC-499 | Mouse Anti-CysLT Recombinant Antibody (clone 14H3); Fab Fragment | ELISA | Mouse Fab |
| PFBC-500 | Mouse Anti-CysLT Recombinant Antibody (clone 2F9); Fab Fragment | ELISA | Mouse Fab |
| PFBC-502 | Mouse Anti-CysLT Recombinant Antibody (clone 9B12); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-497 | Human Anti-CysLT Recombinant Antibody (clone LT5014/Hu10G4); scFv Fragment | ELISA | Humanized scFv |
| PSBC-498 | Mouse Anti-CysLT Recombinant Antibody (clone 10G4); scFv Fragment | ELISA | Mouse scFv |
| PSBC-499 | Mouse Anti-CysLT Recombinant Antibody (clone 14H3); scFv Fragment | ELISA | Mouse scFv |
| PSBC-500 | Mouse Anti-CysLT Recombinant Antibody (clone 2F9); scFv Fragment | ELISA | Mouse scFv |
| PSBC-502 | Mouse Anti-CysLT Recombinant Antibody (clone 9B12); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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