Recombinant human antibody to gp120. The antibody can bind to the JR-FL SOSIP trimer, and poorly or not at all to gp120 monomer. It was highly dependent on the N301 and N332 glycans.
Figure 1 Donor N170 antibodies bind better to JRFL SOSIP gp140 than to JRFL gp120.
ELISA for binding to JRFL SOSIP gp140 or gp120 of donor N170 antibody VRC29.01. Graphs are representative of results from at least two independent experiments. OD, optical density.
Longo, N. S., Sutton, M. S., Shiakolas, A. R., Guenaga, J., Jarosinski, M. C., Georgiev, I. S., ... & Connors, M. (2016). Multiple antibody lineages in one donor target the glycan-V3 supersite of the HIV-1 envelope glycoprotein and display a preference for quaternary binding. Journal of virology, 90(23), 10574-10586.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06); scFv Fragment | Neut, FuncS | Human scFv |
MRO-3634CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone MAG 6B); scFv Fragment | ELISA, RIA | Mouse scFv |
MRO-3635CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone MAG 95); scFv Fragment | ELISA, RIA | Mouse scFv |
MRO-3636CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone MAG 97); scFv Fragment | ELISA, RIA | Mouse scFv |
MRO-3637CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone MAG 3B); scFv Fragment | ELISA, RIA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-546 | Human Anti-HIV-1 gp120 V1V2 domain Recombinant Antibody (clone P4); Fab Fragment | WB, IF, FuncS | Human Fab |
PFBL-547 | Human Anti-HIV-1 gp120 V1V2 domain Recombinant Antibody (clone PG10); Fab Fragment | WB, IF, FuncS | Human Fab |
PFBL-548 | Human Anti-HIV-1 gp120 V1V2 region Recombinant Antibody (clone 830A); Fab Fragment | WB, IF, FuncS | Human Fab |
PSBW-160 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone F105); scFv Fragment | FC, Neut | Human scFv |
PSBW-178 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone b12); scFv Fragment | Neut, ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-028LC-VHH) | ELISA | Single domain antibody |
MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-029LC-VHH) | ELISA | Single domain antibody |
MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-030LC-VHH) | ELISA | Single domain antibody |
MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-031LC-VHH) | ELISA | Single domain antibody |
MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-032LC-VHH) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-005LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-005LC) | ELISA | Human IgG1 |
MRO-006LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-006LC) | ELISA | Human IgG1 |
MRO-007LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-007LC) | ELISA | Human IgG1 |
MRO-011LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-011LC) | ELISA | Human IgG1 |
MRO-012LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-012LC) | ELISA | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-041LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (D59/A2) | ELISA | Mouse antibody |
MRO-042LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (F58/H3) | ELISA | Mouse antibody |
MRO-043LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (P1/D12) | ELISA | Mouse antibody |
MRO-044LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (P4/D10) | ELISA | Mouse antibody |
MRO-045LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (A47/B1) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-3587CQ | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone V3-G2-25) | Neut | Mouse IgG |
MRO-3588CQ | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone V3-W1-2) | Neut | Mouse IgG |
MRO-3589CQ | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone V3-W1-8) | Neut | Mouse IgG |
MRO-3590CQ | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 8F102) | ELISA, FC | Mouse IgG |
MRO-3591CQ | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone D21) | ELISA, Block | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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