Human Anti-HIV-1 gp160 Recombinant Antibody (clone 11-788) (CAT#: MRO-3788CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. 11-788 specifically binds to gp160.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1 Antibody binding to gp140, gp120, gp41, gp160.
Each clonal family is represented by the same color and unique antibodies that are not members of a clonal family are not colored.
Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).
Neut
Figure 2 The neutralizing activity measured by TZM-bl assay is shown for individual antibodies according to their epitopes.
The y-axis shows the IgG antibody concentration required to achieve IC50 for each viruses indicated on the x-axis.
Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).
ELISA
Figure 3 The epitope mapping of 10-188 antibody.
All the experiments were performed at least in duplicate. Error bars indicate the SEM.
Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Recognizes HIV-1 gp160
- Species Reactivity
- HIV-1
- Clone
- 11-788
- Applications
- ELISA, FC, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Neutralization.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
ScFv Antibody Products
Human Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-177) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-178) | WB, ELISA, FuncS | Human IgG |
| PABL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128) | WB, ELISA, FuncS | Human IgG |
| PABL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C) | WB, ELISA, Neut, FuncS | Human IgG, κ |
| PABL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01) | FC, Neut, FuncS | Human IgG |
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