Human Anti-HIV-1 gp160 Recombinant Antibody (clone 11-788) (CAT#: MRO-3788CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. 11-788 specifically binds to gp160.


Specific Inquiry
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  • Published Data
  • Datasheet
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  • COA
FC

Figure 1 Antibody binding to gp140, gp120, gp41, gp160.

Figure 1 Antibody binding to gp140, gp120, gp41, gp160.

Each clonal family is represented by the same color and unique antibodies that are not members of a clonal family are not colored.

Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).

Neut

Figure 2 The neutralizing activity measured by TZM-bl assay is shown for individual antibodies according to their epitopes.

Figure 2 The neutralizing activity measured by TZM-bl assay is shown for individual antibodies according to their epitopes.

The y-axis shows the IgG antibody concentration required to achieve IC50 for each viruses indicated on the x-axis.

Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).

ELISA

Figure 3 The epitope mapping of 10-188 antibody.

Figure 3 The epitope mapping of 10-188 antibody.

All the experiments were performed at least in duplicate. Error bars indicate the SEM.

Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Recognizes HIV-1 gp160
  • Species Reactivity
  • HIV-1
  • Clone
  • 11-788
  • Applications
  • ELISA, FC, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Neutralization.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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