Human Anti-HIV-1 gp160 Recombinant Antibody (clone 45D1/B7) (CAT#: MRO-3750CQ)
Recombinant human antibody to gp160(139-155). This antibody is V1-specific MAb and could potently neutralize autologous strain SF162.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
WB
Figure 3 Oligomeric status of NDV-expressed Env proteins.
DF1 cells were infected with indicated viruses at an MOI of 0.01 PFU. After 48 h, the cells were collected and cross-linked with DSP and subjected to SDS-PAGE under reducing (+R) or non-reducing (-R) conditions.
Khattar, S. K., Samal, S., LaBranche, C. C., Montefiori, D. C., Collins, P. L., & Samal, S. K. (2013). Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector. PloS one, 8(10).
IF
Figure 4 Immunofluorescence of Env protein expressed in Vero cells infected with rLaSota/gp160.
Twenty-four h post-infection, the infected cells were fixed with paraformadehyde and permeabilized with Triton X-100 for detection of total antigen inside the cell.
Khattar, S. K., Samal, S., LaBranche, C. C., Montefiori, D. C., Collins, P. L., & Samal, S. K. (2013). Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector. PloS one, 8(10).
Specifications
- Host Species
- Human
- Type
- Human IgG2, κ
- Specificity
- Recognizes HIV-1 gp160(139-155)
- Species Reactivity
- HIV-1
- Clone
- 45D1/B7
- Applications
- WB, ELISA, Neut, IF
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Neutralization, Immunofluorescence.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- UniProt ID
- P19550
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
ScFv Antibody Products
Human Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-177) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-178) | WB, ELISA, FuncS | Human IgG |
| PABL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128) | WB, ELISA, FuncS | Human IgG |
| PABL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C) | WB, ELISA, Neut, FuncS | Human IgG, κ |
| PABL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01) | FC, Neut, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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