Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 8C6/1) (CAT#: MRO-3840CQ)

Recombinant mouse antibody to gp160(471-490). 8C6/1 preferentially binds SDS-DTT denatured gp120 (>30 fold).

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WB

Figure 1 Comparison of VLP Env and soluble gp120 by BN-PAGE.

Figure 1 Comparison of VLP Env and soluble gp120 by BN-PAGE.

The Env components of various VLPs and soluble gp120 were resolved by BN-PAGE-Western blotting and detected with anti-gp120 and anti-gp41 MAb cocktails.

Tong, T., Osawa, K., Robinson, J. E., Crooks, E. T., & Binley, J. M. (2013). Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120. Journal of virology, 87(16), 9233-9249.

Neut

Figure 2 MAb neutralization of WT and SOS viruses in various assay formats.

Figure 2 MAb neutralization of WT and SOS viruses in various assay formats.

MAb neutralization of WT and SOS JR-FL viruses was evaluated in various neutralization assay formats.

Tong, T., Osawa, K., Robinson, J. E., Crooks, E. T., & Binley, J. M. (2013). Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120. Journal of virology, 87(16), 9233-9249.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Recognizes HIV-1 gp160(471-490)
  • Species Reactivity
  • HIV-1
  • Clone
  • 8C6/1
  • Applications
  • Neut, WB

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Neutralization, Western Blot.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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