Recombinant mouse antibody to gp41. 1d9 was isolated from mice immunized with 2F5-epitope scaffold ES5. 1d9 showed high affinity for both 2F5 epitope and the scaffolds.
Figure 3 Validation of the B ELISpot using the biotinylated 2F5 peptide as a probe to measure epitope specific antigen secreting cells (ASC)
ELISpot plate showing immuno spots generated by the hybridoma cells expressing the murine monoclonal antibody 1D9.
Guenaga, J., Dosenovic, P., Ofek, G., Baker, D., Schief, W. R., Kwong, P. D., ... & Wyatt, R. T. (2011). Heterologous Epitope-Scaffold Prime∶ Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant. PloS one, 6(1).
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• Confirmed specificity
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CAT | Product Name | Application | Type |
---|---|---|---|
MHH-486-S(P) | Recombinant Human Anti-HIV-1 gp41 Antibody scFv Fragment | IF, Neut, FuncS | scFv |
MRO-4048CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 126-50); scFv Fragment | ELISA | Human scFv |
MRO-4049CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 126-6 (SZ-126.6)); scFv Fragment | ELISA, RIA, WB | Human scFv |
MRO-4050CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (MRO-4050CQ-S(P)) | ELISA | Human scFv |
MRO-4051CQ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody scFv Fragment (MRO-4051CQ-S(P)) | Neut | Human scFv |
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