Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone T3) (CAT#: MRO-4182CQ)

Recombinant mouse antibody to gp41. T3 is partially conformation dependent and doesn't bind to short peptides, but does bind to the region spanning 641-683.


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ELISA

Figure 1 gp41 ELISA.

Figure 1 gp41 ELISA.

The result of the IgG gp41 adsorption.

Pietzsch, J., Scheid, J. F., Mouquet, H., Seaman, M. S., Broder, C. C., & Nussenzweig, M. C. (2010). Anti-gp41 antibodies cloned from HIV-infected patients with broadly neutralizing serologic activity. Journal of virology, 84(10), 5032-5042.

ELISA

Figure 2 Binding of Fab m44, 2F5, Z13, and mouse MAbs NC-1 and T3 to 5HB.

Figure 2 Binding of Fab m44, 2F5, Z13, and mouse MAbs NC-1 and T3 to 5HB.

Optical densities (OD) at 405 nm were measured after color development at room temperature for 30 min.

Zhang, M. Y., Vu, B. K., Choudhary, A., Lu, H., Humbert, M., Ong, H., ... & Montefiori, D. C. (2008). Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens. Journal of virology, 82(14), 6869-6879.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • T3
  • Applications
  • ELISA, WB

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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MHC Tetramer for Virology

CAT Product Name Application Type
MHC-LC746 A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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