Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone WR102) (CAT#: MRO-4191CQ)
Recombinant mouse antibody to gp41. WR102 exhibited dual specificity where it can bind to both pure Chol and to pure gp140. WR102 can bind to gp41 but not to gp120. Chol and gp140 each independently contributed with binding energy to WR102.
Specific Inquiry
ELISA
Figure 1 Binding of mAbs to proteins, peptides, and lipids by ELISA.
Binding of WR102 and 2C5-6.
Karasavvas, N., Beck, Z., Tong, J., Matyas, G. R., Rao, M., McCutchan, F. E., ... & Alving, C. R. (2008). Antibodies induced by liposomal protein exhibit dual binding to protein and lipid epitopes. Biochemical and biophysical research communications, 366(4), 982-987.
FuncS
Figure 2 Dose–response of binding of mAbs.
Binding of the indicated amounts of purified 2C6 to the indicated amounts of gp140 alone, or Chol alone,is shown.
Karasavvas, N., Beck, Z., Tong, J., Matyas, G. R., Rao, M., McCutchan, F. E., ... & Alving, C. R. (2008). Antibodies induced by liposomal protein exhibit dual binding to protein and lipid epitopes. Biochemical and biophysical research communications, 366(4), 982-987.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgM
- Specificity
- Recognizes HIV-1 gp41
- Species Reactivity
- HIV-1
- Clone
- WR102
- Applications
- ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Functional Assay. ELISA: For each assay, 100 ng of purified mAb was usedand 10 nmol of Chol, DMPC, or DMPG.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "HIV-1 gp41"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-486-S(P) | Recombinant Anti-HIV-1 gp41 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| MHH-486-S(P) | Recombinant Human Anti-HIV-1 gp41 Antibody scFv Fragment | IF, Neut, FuncS | scFv |
| HPAB-0735-WJ-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (HPAB-0735-WJ-S(P)) | Neut | Human scFv |
| PSBS-0051 | Monkey Anti-HIV-1 gp41 Recombinant Antibody (Clone DH570.4); scFv Fragment | ELISA, Neut, FuncS | Monkey scFv |
| PABJ-0083-S(P) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone VRC42.04); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); Fab Fragment | Neut | Mouse Fab |
| PFBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); Fab Fragment | WB, ELISA | Human Fab |
| PFBC-069 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20); Fab Fragment | Neut, ELISA | Human Fab |
| MRO-4045CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2-1007); Fab Fragment | ELISA | Human Fab |
| MRO-4046CQ-F(E) | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 1-167); Fab Fragment | Neut | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-025LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG3) | ELISA | Human antibody |
| MRO-026LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG1) | ELISA | Human antibody |
| MRO-040LC | Anti-HIV-1 gp41 Recombinant Antibody (M66.6) | ELISA | Human antibody |
| MRO-074LC | Anti-HIV-1 gp41 Recombinant Antibody (W) | ELISA | Human antibody |
| MRO-077LC | Anti-HIV-1 gp41 Recombinant Antibody (3D6) | ELISA | Human antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-842CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1911) | WB | Mouse IgG2a |
| MRO-843CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 191) | WB | Mouse IgG2 |
| MRO-844CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 10E9) | WB, RIPA, ELISA, IF | Mouse IgG1 |
| MRO-845CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 10F6) | ELISA, WB, IP, IF | Mouse IgG2b |
| MRO-846CQ | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1116591) | ELISA | Mouse IgG2a |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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