Recombinant Anti-LGR5 (AA 22-322 x AA 323-558) Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC118)

• Host Animal 1
• Rabbit

• Host Animal 2
• Rabbit

• Specificity
• Human LGR5

• Species Reactivity
• Human, Mouse

• Type
• Tandem scFv

• Valency
• 1 + 1

• Epitope 1
• aa 22-322

• Epitope 2
• aa 323-558

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, FC, IHC, WB

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Leucine Rich Repeat Containing G Protein-Coupled Receptor 5

• Introduction
• LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. LGR5 is expressed across a diverse range of tissue such as in the muscle, placenta, spinal cord and brain and particularly as a biomarker of adult stem cells.

• Alternative Names
• LGR5; leucine-rich repeat containing G protein-coupled receptor 5; FEX; HG38; GPR49; GPR67; GRP49; leucine-rich repeat-containing G-protein coupled receptor 5; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; leucine-rich repeat-containing G protein-coupled receptor 5

• Gene ID
• 8549

• UniProt ID
• O75473

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