Rabbit Anti-LY9 Recombinant Antibody (clone R02-1I0) (CAT#: VS3-FY1985)

• Immunogen
• Recombinant human CD229 protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human LY9

• Species Reactivity
• Human

• Clone
• R02-1I0

• Applications
• Western Blot

• MW
• The calculated weight of the target protein is approximately 72 kDa, while the observed molecular weight stands at 72 kDa.

• Related Disease
• Multisystem Inflammatory Syndrome In Children and Lymphoproliferative Syndrome

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA

• Preservative
• 0.01% Sodium azide

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000

• Alternative Names
• LY9; CD229; SLAMF3; hly9; mlymphocyte antigen 9

• Gene ID
• 4063

• UniProt ID
• Q9HBG7

• Cellular Localization
• Cell membrane, Membrane

• Post Translation Modifications
• Glycosylation at Asn68, Asn95, Asn120, Asn169, Asn173, Asn285, Asn413, and Asn424 (NX_Q9HBG7 [NX_Q9HBG7-1])
  Modification sites at PhosphoSitePlus (Q9HBG7)
  Glycosylation from GlyGen (Q9HBG7) 10 sites, 2 O-linked glycans (1 site)

• Protein Refseq
• XP_011507851.1; XP_011507858.1; XP_011507862.1; XP_016856788.1; XP_016856790.1

• Function
• Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody